image

ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

image
image
Lourdes de Fatima Ibanez Valdes
Department of Neurology, Nelson Mandela Academic Central Hospital (NMACH), Walter Sisulu University, Mthatha, South Africa

Publications

  • Research Article   
    Combined Central and Peripheral Demyelinating Spectrum Disorder: A Case Report and Systematic Review
    Author(s): Lourdes de Fatima Ibanez Valdes and Humberto Foyaca Sibat*

    Background: Combined Central and Peripheral Demyelination (CCPD) disorders are composed of uncommon clinical pathologies characterized by central and peripheral nervous system inflammatory processes of the Myelin Sheath (MS). Clinical features of CCPD are atypical for MS, with a lack of oligoclonal immunoglobulin G bands causing CCPD target nodes and paranodes of a node of Ranvier in the CNS/PNS and an associated anti-neurofascin antibody. The previous report about the speed recovery after anti-CD20 monoclonal antibody-Rituximab therapy has not been published. Methods: We searched the medical literature for articles on CCPD and other autoimmune-mediated peripheral neuropathies between January 01, 2012, and January 01, 2022, following our inclusion/exclusion criteria. The relevant information was extracted from each publication using Microsof.. Read More»
    DOI: 10.3371/CSRP.DLHF.011023

    Abstract HTML PDF