ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

Vasavi Gorontla
Department of Anatomical Sciences, St. Georges University School of Medicine, Grenada, West Indies


  • Review Article   
    Long-Term Potentiation (LTP): A Simple yet Powerful Cellular Process in Learning and Memory
    Author(s): Sabyasachi Maity, Sareesh Naduvil Narayanan, Richard M Millis, Rashmi K and Vasavi Gorontla*

    Learning and memory are natural responses of the body to assist us in living. Neurodegenerative diseases wreak havoc on the neuronal processes that control memory development and consolidation, causing mental, social, and financial hardship for millions of people around the world. In the mammalian brain, many neurotransmitters are involved in memory formation and consolidation. The cellular mechanisms and signaling pathway involved in this, however, are not fully understood. Donald Hebb suggested the synaptic reorganization hypothesis in support of memory development decades ago. Two types of synaptic plasticity, Long-Term Potentiation (LTP) and Depression (LTD), have been implicated in the formation and consolidation of memory in mammalian brains as a result of the advancement of modern electrophysiology and molecular biology techniques. The synapses are also though.. Read More»

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