ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

Shivkant Sharma
Assistant Professor, Department of Pharmaceutical sciences, Gurugram University, Gurugram -122018, India


  • Review Article   
    A "Review" on Brain Disorder Schizophrenia
    Author(s): Shivam Vashist*, Shivkant Sharma and Dhirender Kaushik

    Studies on the Pathophysiology of schizophrenia are based on disorders in neurotransmission. The majority of these hypotheses focus on neurotransmitters like dopamine, serotonin, and glutamate, whether in excess or insufficiently. Other hypotheses link the neurochemical imbalance of schizophrenia to aspartate, glycine, and Gamma-ASminobutyric Acid (GABA). [1]. Many of the symptoms of schizophrenia are likely to be accompanied with abnormal dopamine receptor site activity, notably D2 receptor activity [2,3]. The caudate nucleus serves as the destination for the nigrostriatal pathway, which begins in the substantia nigra. It is believed that low dopamine levels in this pathway have an impact on the extrapyramidal system and cause motor symptoms [1]. In the presence of excessive dopamineThe Ventral Tegmental Area (VTA) and limbic regions are linked through the mesolimbic pathway, which m.. Read More»
    DOI: 10.3371/CSRP.MMWY.100131

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