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ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

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Mona N. Al-Terehi
Department of Biology, University of Babylon College of Medicine, Babylon, Iraq

Publications

  • Research   
    The RAD-18 Arg302Gln (rs373572) and OGG1 Ser326Cys (rs1052133) Genes Polymorphisms in Systemic Lupus Erythematous Disease
    Author(s): Noora M. Hameed*, Sawsam Jassim Al-Harbi, Hadeel Alaa Al-Rrubaei and Mona N. Al-Terehi

    The Systemic Lupus Erythematous (SLE) disease is an autoimmune disease incidence by different genetic and environment factors, the present research study two DNA repair genes polymorphisms in SLE disease included RAD-18 Arg302Gln (rs373572) and OGG1 Ser326Cys (rs1052133) genes, the polymorphisms were detection using allele specific PCR and PCR-SSCP, patients were diagnostic by specialist physician then DNA was isolated from whole blood, the results show that The RAD-18 gene variation show non-significant differences between patients and control, tow genotyping (AA and AG) were observed and GG didn’t observed, the distribution of AA and AG were 95.29% of patients have AA while 92.85% in control GG appeared in 4.76% of patients and 7.14% in control (OR 0.6667, P value 0.6936). The OGG1 Ser326Cys (rs1052133) genes polymorphisms shows the.. Read More»

    Abstract PDF