ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

Ghazi Faisal Majid
Pharmacology and Toxicology Department, Mustansiriyah University, College of Pharmacy, Baghdad, Iraq


  • Research   
    Potential Effect of Botulinum Neurotoxin A in the Treatment of Induced Benign Prostatic Hyperplasia in Male Rats
    Author(s): Ghazi Faisal Majid*, Mustafa Ghazi Alabbassi and Israa B. Raof

    Background: Researches carried out in humans, dogs, and rats showed that the injection of botulinum neurotoxin type A into the prostate gland reduce the size and other biomarker that indicate botulinum neurotoxin type A as a new promising treatment for benign prostatic hyperplasia. Aim of the research: The purpose of the study is to evaluate the effects of botulinum neurotoxin type A in the treatment of induced BPH rat model, comparing it with the most powerful standard treatment available composed of alfuzosin and dutasteride (combination of α1 adrenergic antagonist and 5α reductase inhibitor) for BPH rat model and also to describe the mechanism by which botulinum neurotoxin type A effect prostate growth by focusing on acetylcholine-prostate nicotinic receptor signal role in BPH. Method: Five g.. Read More»

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