Castillo RL

Department of Internal Medicine East Division, School of Medicine, Universidad de Chile, Santiago, Chile

Publications

• Review Article   
  Schizophrenia as a complex neuromedical disease
  Author(s): Orellana Gricel* and Castillo RL
  
  Introduction: Schizophrenia (SZ) is a severe chronic psychiatric disease that significantly affects individuals’ quality of life. The life expectancy of patients with SZ is 11 to 30 years less than that of the general population. An association between SZ and a range of comorbid chronic diseases and conditions, including cardiometabolic diseases, has been discovered, which in part explains the decrease in life expectancy and quality of life. This association has been linked to the use of antipsychotics. However, scientific evidence has also demonstrated that SZ patients are intrinsically susceptible to developing chronic diseases. Moreover, the link between cardiometabolic risk and the time course of SZ evolution has not been explored. Method: The authors reviewed 147 papers to provide an update on chronic cardiometabolic diseases and sleep, bone, kidney, and cancer alterations .. Read More»
  

  Abstract PDF