Abstract
The Insulin and Glycemic Parameters Role in the Sleep and Depression Disorders in Diabetes Mellitus Type 2 Patients
Author(s): Waleed Azeez AlAmeedy, Taha H. Alnasrawi, Zainab A. Mahdi, Tawfeeq Alghazali, Ahlam Kadhim Hussein, Muneam Hussein Ali, Hajer Ali Enad, Karrar A. Zwain* and Ali Jali ObaidThe role of insulin and glycemic parameters have been well described in diabetes mellitus and its complications, in this study the relation of sleep disorder with insulin and glycemic parameters were detected in Diabetes Mellitus Patients Type 2(DM2) and DM2 suffered from Depression Disorder (DD), the glycemic parameters including (Fasting Blood Glucose (FBG), glycated protein (HbA1c), Insulin Resistance (IR) and Insulin Sensitivity (IS) and Insulin Level (IN) were detected. Results show that sleep duration in DM2 and DM2 with DD were in non-significant differences among groups, the DM group having less than 6 hours of sleep was lower percentage than DM2 with DD and control groups. significant changes in all glycemic parameters and insulin level were observed among groups, non-significant changes of all study variables between>6 hours and<6 hours subgroups excepted the FBG in the control group that has significant changes (p=0.009), the correlation of sleep duration with IN and glycemic parameters show non-significant changes in DM2, DM2 with DD in comparison with the control group, there was weak positive correlation between sleep and FBG, IR in DM2 with DD and weak inverse with DM2, positive correlation with IS in DM2, and strong association with IN in DM2 with DM and inverse correlation in DM2. The study concluded that glycemic parameters didn’t associate with sleep duration, but insulin may contribute to the sleep duration in DM and DM2 with DD according to its correlation in study groups.