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ISSN: 1935-1232 (P)

ISSN: 1941-2010 (E)

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Abstract

The Combined Psychoactive Effects of Caffeine, Nicotine and MDMA on the Prefrontal Cortex of Juvenile Experimental Male Wistar Rats
Author(s): Victor C Ogbolu, Sunday O Fabiyi, Olubunmi E Ogunbiyi and Joshua O Owolabi

The developing brain at the adolescent stage is prone to the effects of various psychoactive agents and environmental influences. Caffeine, nicotine and MDMA influences on the developing brain and the possible consequences of such on fundamental mental attributes that determine brain health primarily including memory, cognition, behavior and learning among others. This research studied the structural and functional changes attributable to the combined use of caffeine, nicotine and MDMA on the prefrontal cortex including learning, cognition and anxiety tendencies.