Solitary Sclerosis: Is it a New Disease in the Category of Connectomopathy?Author(s): Abdorreza Naser Moghadasi*
Connectomopathy is a novel term referred to a set of diseases in which not only the whole brain connectome is involved, but also the damaged connectome itself acts as a context for the progression of these diseases. The best example of connectomopathy is Multiple Sclerosis (MS), which is caused by the malfunction of the immune system. Solitary Sclerosis (SS) is a rare disease, which progresses in patients following a solitary demyelinating lesion and then becomes incapacitated despite using various medications. Few studies have indicated that the pathology is not limited only to the lesion and would involve a large area in the brain. The present study aimed to address more aspects of connectomopathy by addressing SS as a relatively new term in the inflammatory diseases related to the CNS.