Neuromyelitis Optica Spectrum Disorder Associated with Arterial Hypertension and Pityriasis Versicolor. A Novel Presentation?Author(s): Sibi Joseph, Lourdes de Fátima Ibañez-Valdé and Humberto Foyaca-Sibat*
Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare antibody-mediated disease of the CNS causing astropathy and leading to demyelination. It typically does affect the optic nerves and the spinal cord, especially in long segments, but other features are helpful for the diagnosis.
The disease has been reported to have associations with dermatological conditions such as pruritus and eczematous changes; this is thought to be because the skin and the CNS both have the same water channels, AQP4. Other reports have been made associating NMOSD with hypertension, as a side effect of the drugs or as comorbidity.
We report a young lady who showed NMOSD and previously unreported skin condition in association with it: Pityriasis versicolor and hypertension in the young simultaneously. Based upon our literature review, we have not seen these three conditions in any one patient and hence felt it would be a noteworthy addition to the body of knowledge of this rare disorder.