Clinical Assessment of Oral Curcumin Adjuvant in Post-Ischemic Stroke PatientsAuthor(s): Ali Bayyat Abed and Manal Khalid Abdulridha*
Background: The assessment of effectiveness curcumin in patients with ischemic stroke is limited in human studies.
Methods: Prospective randomized -controlled open -labeled single -center study was conducted on post stroke patients with or without history of comorbidity from both genders. The eligible patients were allocated into two groups; Group 1 patients on conventional therapy of post-acute ischemic stroke, and group 2:Patients on conventional therapy of post-acute ischemic stroke plus 750 mg Curcumin two capsule single dose daily(1500mg) for 3 months. Muscle Power Scale (MRC), Activism-Stroke Scale, Stroke Specific Quality of Life (SSQOL), and SBP was measured
Results: The results in the present study revealed significant improvement up to (71.30%) in muscle power scale in patients with curcumin adjuvant when compared to convention improvement activity of patients' daily activities, particularly items from 3 to 14 scaling to the most difficult (carrying a heavy bag), improvement SSQOL questionnaire specific domains like(energy, mobility, thinking, extremity function and work productivity), (p<0.01), also significant decrease in SBP after 3 months of treatment(p<0.05).
Conclusion: The improvement in patients' daily activities and subsequent quality of life among patients with post ischemic stroke received curcumin adjuvant treatment. More clinical research can provide new insight into the treatment of stroke with curcumin.